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• Micro PET/CT

MicroPET/CT is basically the same technology as PET/CT; however, it is designed to capture the brain image of small animals like rats. MicroPET offers a unique opportunity to image small animal models of diseases, including those of genetically engineered animals. It is a functional imaging modality at the molecular level and provides valuable in vivo insights into biochemical, physiological, pathological, and pharmacological processes. Data can be obtained noninvasively, repeatedly, and quantitatively in the same animal. MicroPET is currently applied to diverse fields of research including perfusion, metabolism, and substrate utilization in various vital organs including the heart and brain, gene expression and stem cell tracking, neurotransmitters and receptors, neural activation and plasticity, targeting tumor antigens, and elucidating tumor biology such as angiogenesis, hypoxia, and apoptosis. Recent research efforts have applied microPET to a wide area of study ranging from basic insights into normal physiological and disease processes, drug development, and the early response to anticancer and gene therapies. Research can also be conducted in the field of imaging physics and scanner development, image and data analysis, attenuation correction and reconstruction techniques, and tracer kinetics and modeling.

The microPET R4 scanner for the scanning of rats and mice has an 8 cm axial field of view and < 2.0 mm spatial resolution. It also includes a dual 1 GHz Pentium PC. A second PC (Dual 600 MHz) is available for microPET data analysis and iterative reconstruction using OSEM. A LINUX machine is available for other iterative reconstruction methods like MAP and MLEM.

Link to Animal and Molecular Imaging Research