We are conducting research on microvascular anomalies particularly in early stage of stroke by enabling human research without invasive procedures through microvascular imaging of the brain using 7T MRA of ultra-high magnetic intensity. Ultimately, we are aiming to develop the early diagnosis and treatment of cerebrovascular diseases, which need knowledge of basic image engineering. Therefore, we are closely collaborating with the research team of image engineering such as teams of MRI, single photon emission tomography (SPECT), and positive electron emission tomography (PET). The outcome of our collaboration will be the discovery of the differences between the vascular structure of normal subjects and patients, which will serve as the basis for understanding the pathogenesis of cerebrovascular diseases, and developing technology of early diagnosis and treatment of them.